4-AcO-MET 20 MG Pellets – Research Substance from the Tryptamine Family

Product Name: 4-AcO-MET (4-acetoxi-N-etyl-N-metyltryptamin)
Form: Pressed pellets, 20 mg each
Chemical Class: Psychedelic tryptamine
Molekylformel: C15H22N2O2
Molecular Mass: 262.35 g/mol
Renhet: ≥98% (verified by HPLC and NMR)
Uses: For analytical research and laboratory use only

Description

4-AcO-MET is a semi-synthetic tryptamine structurally related to both psilocin and 4-AcO-DMT. It is often considered a prodrug of MET (N-ethyl-N-methyltryptamine), a substance with serotonergic activity. In research settings, 4-AcO-MET is known for its interesting pharmacological properties and relatively mild, yet significant visual and cognitive effects in experimental models.

The 20 MG-pellets provide standardized and accurate dosing for laboratories analyzing this substance for stability, interaction with serotonin receptors, or structural comparison to related tryptamines.

Applications in Scientific Research

🔬Receptor binding studies (particularly 5-HT2A, 5-HT1A)
🔬Comparative tryptamine research: structural and pharmacological relationships
🔬Visualization of neurobiological processes in animal models
🔬Prodrug analysis and metabolism (from 4-AcO-MET to MET)
🔬LC-MS and GC-MS reference standard for analytical laboratories

Benefits for Researchers

✅ Standardized pellet dosing – Minimizes weighing errors in microdosing experiments
✅ Mild and controllable pharmacological properties
✅ Interesting prodrug structure – Study of metabolism and enzymatic conversion
✅ High purity and stability – Ideal for replication of results

Disadvantages and Possible Limitations

⚠️ Light sensitive – Should be stored in the dark
⚠️ Limited long-term data – Limited clinical literature on toxicological properties
⚠️ Potentially unpredictable effects in animal models at higher doses
⚠️ Not suitable for use outside a controlled research environment

Recommended Laboratory Use

• Starting dose for in vitro testing: 1–5 mg dissolved in ethanol or aqueous buffer
• For binding experiments: 10–20 µM concentration in cell culture medium
• Löslighet: Good in ethanol, moderate in water
• Storage: Store in a dry, airtight container and cool (preferably < 8°C).

Laboratory Report – Batch Data

Vanliga frågor (FAQ)

❓ Is 4-AcO-MET legal in the Netherlands or Belgium?

➡️The status is a gray area . Not regulated under the Opium Act, but prohibited for human consumption. Permitted only for authorized research.

❓ What is the difference between 4-AcO-MET and 4-AcO-DMT?

➡️4-AcO-MET contains an N-ethyl group instead of a dimethyl group. This may lead to subtly different pharmacological effects, generally with milder visual intensity.

❓ How should I handle the pellets in the lab?

➡️Use gloves and milligram-accurate scales. Wear a lab coat and work under a fume hood when dissolving or handling the material.

❓ Can 4-AcO-MET be stored long-term?

➡️Yes, as long as it’s stored airtight and cool. For optimal stability, store in a dark jar below 8°C.

❓ Is 4-AcO-MET converted to MET in the body?

➡️Animal models have shown that 4-AcO-MET is converted to MET by hydrolysis, making it a prodrug. This makes it interesting for metabolic research.

Warning

⚠️ For use only by qualified researchers in accredited laboratories. Not for consumption, diagnostics, therapeutic use, or household use.