{"id":23373,"date":"2025-04-13T17:39:38","date_gmt":"2025-04-13T17:39:38","guid":{"rendered":"https:\/\/researchchemicallab.eu\/?post_type=product&p=23373"},"modified":"2026-02-03T11:34:06","modified_gmt":"2026-02-03T11:34:06","slug":"escaline-fumarate","status":"publish","type":"product","link":"https:\/\/researchchemicallab.eu\/en\/shop\/almost-forbidden\/escaline-fumarate\/","title":{"rendered":"Escaline fumarate"},"content":{"rendered":"

Escaline Fumarate \u2013 Innovative Psychedelic Phenethylamine for Scientific Research<\/strong><\/h1>\n

Product name:<\/strong> Escaline Fumarate
\nFull Name:<\/strong> 3,5-dimethoxy-4-ethoxyphenethylamine fumarate
\nChemical Class:<\/strong> Psychedelic phenethylamine
\nMolecular formula (fumarate salt):<\/strong> C12H19NO3 C4H4O4
\nMolecular mass:<\/strong> \u00b1 325.34 g\/mol
\nAppearance:<\/strong> White to light yellow powder (crystalline)
\nPurity:<\/strong> \u2265 98% (tested via HPLC & NMR)
\nSynonyms:<\/strong> Escaline hemi-fumarate, 4-ethoxy-mescaline<\/p>\n

\n

\ud83e\uddec What is Escaline Fumarate?<\/strong><\/h2>\n

Escaline is a psychedelic phenethylamine<\/strong> and a structural analogue of mescaline, with a ethoxy group<\/strong> instead of a methoxy at the 4-position. The fumarate version (salt form) offers improved stability and solubility<\/strong>, ideal for precise laboratory analysis.<\/p>\n

\u26a0\ufe0f For analytical and pharmacological research only. Not for human consumption.<\/em><\/p><\/blockquote>\n

\n

\ud83d\udd2c Applications in Research<\/strong><\/h2>\n

Escaline is being investigated for his agonistic effect on serotonergic receptors<\/strong> (especially 5-HT2A), and its structural similarity to classical psychedelics.<\/p>\n

Possible applications:<\/h3>\n
    \n
  • Receptor binding studies<\/strong> in serotonergic pathways<\/li>\n
  • Neurochemical comparative study<\/strong> with mescaline, proscaline and isoproscaline<\/li>\n
  • Pharmacokinetic simulations<\/strong> and SAR (structure-activity relationship) analyses<\/li>\n
  • In vitro consciousness modeling<\/strong> via cell lines and receptor analysis methods<\/li>\n<\/ul>\n
    \n

    \ud83e\uddea Use and Laboratory Instructions<\/strong><\/h2>\n
      \n
    • Solubility:<\/strong> Freely soluble in ethanol, DMSO; moderately soluble in water<\/li>\n
    • Recommended concentration (in vitro):<\/strong> 5\u201330 \u00b5M depending on assay type<\/li>\n
    • Save:<\/strong> Dry, airtight and at 2\u20138 \u00b0C<\/li>\n
    • Form:<\/strong> Hemi-fumarate (1:0.5 ratio Escaline:fumarate)<\/li>\n
    • PPE recommended:<\/strong> Gloves, goggles, working under draught extraction<\/li>\n<\/ul>\n
      \n

      \u274c Disadvantages and Risks<\/strong><\/h2>\n

      Although Escaline is valuable for scientific research, there are some limitations:<\/p>\n

        \n
      • Limited research:<\/strong> Very little peer-reviewed data available<\/li>\n
      • Psychoactive profile:<\/strong> Possible strong effect in case of accidental exposure<\/li>\n
      • Legislation:<\/strong> Possibly illegal under analogue legislation (NL\/BE\/EU)<\/li>\n
      • Structure sensitivity:<\/strong> Small molecular changes can dramatically alter biological responses<\/li>\n<\/ul>\n
        \n

        \ud83d\udcca Sample Laboratory Analysis<\/strong><\/h2>\n

        Batch code:<\/strong> ESC-FUM-2025-07
        \nTested by:<\/strong> DeltaChem Scientifics BV
        \nDate analysis:<\/strong> 2025-06-10<\/p>\n\n\n\n\n\n\n\n\n\n
        Analysis method<\/th>\nResult<\/th>\n<\/tr>\n<\/thead>\n
        HPLC<\/td>\n98.6% purity<\/td>\n<\/tr>\n
        NMR spectroscopy<\/td>\nIdentity confirmed<\/td>\n<\/tr>\n
        FTIR<\/td>\nFunctional groups according to<\/td>\n<\/tr>\n
        GC-MS<\/td>\nNo impurities detected<\/td>\n<\/tr>\n
        Heavy metals<\/td>\nNot detectable (<0.01%)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
        \n

        \u2753 Frequently Asked Questions (FAQ)<\/strong><\/h2>\n

        What exactly does Escaline do?<\/h3>\n

        Escaline is probably a 5-HT2A agonist<\/strong>, like mescaline, resulting in changes in perception and consciousness. However, the exact pharmacodynamics are still incompletely studied.<\/p>\n

        Is Escaline legal in the Netherlands?<\/h3>\n

        Possibly not.<\/strong> Although it is often not specifically mentioned, it can be analogue legislation<\/strong> fall. Legal advice is recommended.<\/p>\n

        Is Escaline the same as mescaline?<\/h3>\n

        No.<\/strong> It is an analogue: Escaline contains a ethoxy group<\/strong> instead of the 4-methoxy group of mescaline, which affects potency and binding profile.<\/p>\n

        Can I test or experience Escaline myself?<\/h3>\n

        No.<\/strong> This product is intended for use only professional laboratory use<\/strong> and is not approved for human consumption<\/strong>.<\/p>\n

        Why is it supplied as fumarate?<\/h3>\n

        The fumarate form<\/strong> offers:<\/p>\n

          \n
        • Better chemical stability<\/strong><\/li>\n
        • Less hygroscopic behaviour<\/strong><\/li>\n
        • Simpler dosage management<\/strong> in research environments<\/li>\n<\/ul>\n
          \n

          \u26a0\ufe0f Legal and Safety Disclaimer<\/strong><\/h2>\n

          Not for consumption.<\/strong> Available only to academic institutions, research facilities and accredited laboratories. Sale to minors is prohibited. Manufacturer and seller assume no liability for misuse.<\/p>","protected":false},"excerpt":{"rendered":"

          Escaline fumarate properties<\/h3>\n

          Synonym:<\/strong> 3,5-dimethoxy-4-ethoxyphenethylamine fumarate
          \nCAS Number:<\/strong> 39201-82-6
          \nFormula:<\/strong> 2-{3,5-dimethoxy-4-ethyloxyphenyl}ethan-1-amine fumarate
          \nMolar mass:<\/strong> 341.4 g\/mol
          \nPurity:<\/strong> >97%<\/p>","protected":false},"featured_media":29036,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[322,535,80],"product_tag":[326],"class_list":{"0":"post-23373","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-bijna-verboden","7":"product_cat-escaline","8":"product_cat-fenethylamine","9":"product_tag-nl","11":"first","12":"instock","13":"taxable","14":"shipping-taxable","15":"purchasable","16":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/researchchemicallab.eu\/en\/wp-json\/wp\/v2\/product\/23373","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicallab.eu\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicallab.eu\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicallab.eu\/en\/wp-json\/wp\/v2\/comments?post=23373"}],"version-history":[{"count":4,"href":"https:\/\/researchchemicallab.eu\/en\/wp-json\/wp\/v2\/product\/23373\/revisions"}],"predecessor-version":[{"id":28857,"href":"https:\/\/researchchemicallab.eu\/en\/wp-json\/wp\/v2\/product\/23373\/revisions\/28857"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicallab.eu\/en\/wp-json\/wp\/v2\/media\/29036"}],"wp:attachment":[{"href":"https:\/\/researchchemicallab.eu\/en\/wp-json\/wp\/v2\/media?parent=23373"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicallab.eu\/en\/wp-json\/wp\/v2\/product_brand?post=23373"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicallab.eu\/en\/wp-json\/wp\/v2\/product_cat?post=23373"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicallab.eu\/en\/wp-json\/wp\/v2\/product_tag?post=23373"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}